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ARGX-119
go.drugbank.com/drugs/DB18133InvestigationalARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSKSatricabtagene autoleucel
go.drugbank.com/drugs/DB18288InvestigationalSatricabtagene autoleucel is an autologous CAR T-cell product candidate against protein Claudin18.2 (CLDN18.2).
ISB 2001
go.drugbank.com/drugs/DB18570InvestigationalISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.
ISTH0036
go.drugbank.com/drugs/DB18606InvestigationalISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA
BVX-001
go.drugbank.com/drugs/DB18733ExperimentalBVX001 is a a novel, first-in-class CD33/CD7-directed antibody-drug conjugate.
AZD-7268
go.drugbank.com/drugs/DB19203InvestigationalAZD-7268 is under investigation in clinical trial NCT01020799 (AZD7268 Safety and Tolerability Study).
Synonyms: Benzamide, n-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-, N-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-benzamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingOXB-301
go.drugbank.com/drugs/DB19269InvestigationalOXB-301 is under investigation in clinical trial NCT00397345 (Trovax Renal Immunotherapy Survival Trial).
7MW3711
go.drugbank.com/drugs/DB19298InvestigationalDeveloped by Mabwell, 7MW3711 is an antibody-drug conjugate targeting B7-H3.[L50918,L50923]
Onfekafusp alfa
go.drugbank.com/drugs/DB16269InvestigationalOnfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Synonyms: Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor necrosis factor .alpha., trimerTPCA-1
go.drugbank.com/drugs/DB17058ExperimentalTPCA-1 is a selective inhibitor of human IκB kinase 2 (IKK-2).[A253152]
Synonyms: 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide, 3-thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-Categories: Heterocyclic Compounds, 1-Ring