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Displaying results 6791 - 6800 of 10000 in total
  1. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

  2. Drug

    Apomab

    go.drugbank.com/drugs/DB15022
    Investigational

    Apomab is under investigation in clinical trial NCT00851136 (A Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previously Untreated, Locally Advanced

  3. Drug

    Desmethylprodine

    go.drugbank.com/drugs/DB01478
    ExperimentalIllicit

    It has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. … Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine.

  4. Drug

    Osoresnontrine

    go.drugbank.com/drugs/DB16274
    Investigational

    in Patients With Schizophrenia on Stable Antipsychotic Treatment.). … Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks

  5. Drug

    BZL101

    go.drugbank.com/drugs/DB05051
    Investigational

    BZL101 is an oral drug designed for the treatment of advanced breast cancer with a novel mechanism of action. BZL101 targets diseased cells while leaving normal cells healthy and intact.

    Categories: Complex Mixtures
  6. Drug

    Heptabarbital

    go.drugbank.com/drugs/DB01354
    Experimental

    Heptabarbital is an intermediate or short term barbiturate used mainly for sedation and hypnosis.

  7. Drug

    Ad5-nCoV

    go.drugbank.com/drugs/DB15655
    Investigational

    )[L12675] with an expected completion in December 2020. … [L12675,L12678] It is being developed by CanSino Biologics Inc., in partnership with the Beijing Institute of Biotechnology, who in March 2020 announced the approval of a phase I clinical trial (ChiCTR2000030906

  8. Drug

    α-Methylacetylfentanyl

    go.drugbank.com/drugs/DB01532
    ExperimentalIllicit

    anhydride for the production of chemical propionic anhydride in the synthesis. … It was categorized under the Schedule I in the US and it was illegally sold in early 1980. α-Methylacetylfentanyl synthesis process is very similar to α-methylfentanyl with the substitution of the acetic

  9. Drug

    Tozasertib

    go.drugbank.com/drugs/DB19675
    Investigational

    Tozasertib is under investigation in clinical trial NCT02532868 (A VX-680 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Cancer (0457-002)). … The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor.

  10. Drug

    Zelicapavir

    go.drugbank.com/drugs/DB21662
    Investigational

    Zelicapavir is under investigation in clinical trial NCT06601192 (A Study to Investigate the Effects of Zelicapavir (EDP-938) on QTc Interval in Healthy Adults). … The usage of the INN stem '-capavir' in the name indicates that Zelicapavir is a viral capsid and nucleocapsid inhibitor.