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Setileuton
go.drugbank.com/drugs/DB19550InvestigationalSetileuton is a small molecule drug. The usage of the INN stem '-leuton' in the name indicates that Setileuton is a 5-lipo-oxygenase inhibitor, anti-inflammatory. … Setileuton is under investigation in clinical trial NCT00404313 (The Effect of MK0633 in Patients With Chronic Asthma (0633-007)). Setileuton has a monoisotopic molecular weight of 463.12 Da.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingGTI-2501
go.drugbank.com/drugs/DB05406ExperimentalThe drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. … GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial.
AZD 3355
go.drugbank.com/drugs/DB05404InvestigationalAZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.
Categories: GABA-A Receptor AgonistsD-Glutamic Acid
go.drugbank.com/drugs/DB02517ExperimentalGlutamic acid is the most common excitatory neurotransmitter in the central nervous system.
Synonyms: D-Glutamic AcidAV608
go.drugbank.com/drugs/DB05072InvestigationalAV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Bucainide
go.drugbank.com/drugs/DB20650ExperimentalBucainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Bucainide is a class I antiarrhythmic, procainamide and lidocaine derivative. … Bucainide has a monoisotopic molecular weight of 329.28 Da.
Categories: Heterocyclic Compounds, 1-RingCinuperone
go.drugbank.com/drugs/DB19498ExperimentalCinuperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Cinuperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative. … Cinuperone has a monoisotopic molecular weight of 377.19 Da.
Declenperone
go.drugbank.com/drugs/DB19700ExperimentalDeclenperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Declenperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative. … Declenperone has a monoisotopic molecular weight of 381.19 Da.
Dasantafil
go.drugbank.com/drugs/DB19918ExperimentalDasantafil is a small molecule drug. The usage of the INN stem '-afil' in the name indicates that Dasantafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. … Dasantafil has a monoisotopic molecular weight of 521.13 Da.
Tauromustine
go.drugbank.com/drugs/DB19978ExperimentalTauromustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Tauromustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. … Tauromustine has a monoisotopic molecular weight of 286.05 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates