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Displaying results 6851 - 6860 of 10000 in total
  1. Drug

    Alpibectir

    go.drugbank.com/drugs/DB21561
    Investigational

    Alpibectir is under investigation in clinical trial NCT06748937 (A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide). … Alpibectir has a monoisotopic molecular weight of 332.1 Da.

  2. Drug

    Ceperognastat

    go.drugbank.com/drugs/DB21591
    Investigational

    Ceperognastat is under investigation in clinical trial NCT05063539 (A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease). … Ceperognastat has a monoisotopic molecular weight of 383.14 Da.

  3. Drug

    Ranosidenib

    go.drugbank.com/drugs/DB21727
    Investigational

    Ranosidenib is a small molecule drug. Ranosidenib is under investigation in clinical trial NCT06387069 (A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid Leukemia). … Ranosidenib has a monoisotopic molecular weight of 453.12 Da.

  4. Drug

    IN01

    go.drugbank.com/drugs/DB16434
    Experimental

    Of note, the IN01 vaccine is being tested in a Phase I clinical trial in patients with fibrosing interstitial lung disease resulting from SARS-CoV-2 infection (NCT04537130). … The study will explore the effect of this vaccine on pulmonary function, oxygen saturation, quality of life, and fibrosing status in addition to biomarkers and molecular markers of the vaccine.

  5. Drug

    Pegvisomant

    go.drugbank.com/drugs/DB00082
    ApprovedInvestigational

    Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly.

  6. Drug

    Avasopasem manganese

    go.drugbank.com/drugs/DB16354
    Investigational

    [L27246, L27256] This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19. … Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.

  7. Drug

    Inaxaplin

    go.drugbank.com/drugs/DB21521
    Investigational

    Inaxaplin is under investigation in clinical trial NCT06794996 (Phase 2b Open-label Study of Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease). … Inaxaplin has a monoisotopic molecular weight of 417.13 Da.

  8. Drug

    Recanaclotide

    go.drugbank.com/drugs/DB15417
    Investigational

    Recanaclotide is under investigation in clinical trial NCT01712412 (Phase 2a Study of IW-9179 to Treat Functional Dyspepsia).

  9. Drug

    Mivebresib

    go.drugbank.com/drugs/DB21300
    Investigational

    The usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic. … Mivebresib is under investigation in clinical trial NCT04480086 (Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants

  10. Drug

    Zeteletinib

    go.drugbank.com/drugs/DB21491
    Investigational

    Zeteletinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Zeteletinib is a tyrosine kinase inhibitor. … Zeteletinib is under investigation in clinical trial NCT03780517 (Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors).