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Anetumab ravtansine
go.drugbank.com/drugs/DB14809InvestigationalAnetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Anti-mesothelin antibody-drug conjugate BAY 94-9343KW-7158
go.drugbank.com/drugs/DB05498ExperimentalThe therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion … KW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity
IBIO-100
go.drugbank.com/drugs/DB18233ExperimentalIBIO-100 is a high molecular weight multimer of E3-Fc, an endostatin C-terminus and IgG1-Fc fusion protein.
Bardoxolone
go.drugbank.com/drugs/DB12651InvestigationalBardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. … It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic
Nequinate
go.drugbank.com/drugs/DB11433ExperimentalVet approvedNequinate is an antiprotozoan used as a coccidiostat for poultry and rabbits. Nequinate belongs to the family of Hydroquinolones. … These are compounds containing an hydrogenated quinoline bearing a ketone group.
VAD-044
go.drugbank.com/drugs/DB17697InvestigationalVAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098]
Tabalumab
go.drugbank.com/drugs/DB11657InvestigationalTabalumab has been used in trials studying the treatment of Autoimmune Disease, Rheumatoid Arthritis, Kidney Failure, Chronic, Connective Tissue Disease, and Systemic Lupus Erythematosus, among others.
Categories: Amino Acids, Peptides, and ProteinsVosilasarm
go.drugbank.com/drugs/DB13939InvestigationalRAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.
Galegenimab
go.drugbank.com/drugs/DB18860InvestigationalGalegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to … Age-related Macular Degeneration (AMD)).