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Xylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity. … [A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.
Mixtures: Otrivin Duo 0,5 mg/ml + 0,6 mg/ml Nasenspray, Lösung, NASOVİNE DUO 0,5 MG + 0,6 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADETProducts: Otrivin With M-D PumpTrifluridine
go.drugbank.com/drugs/DB00432ApprovedInvestigationalIt is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. … anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.
Methyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalA synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methylt...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSodium lauryl sulfate
go.drugbank.com/drugs/DB00815ApprovedSodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.
Mixtures: Medi Hydro DP Cleanser, Trimo SanCetyl alcohol
go.drugbank.com/drugs/DB09494ApprovedDue to its water-binding property, cetyl alcohol is commonly used as an emollient that prevents drying and chapping of the skin [A32209]. … It can be produced from the reduction of palmitic acid.
Pibrentasvir
go.drugbank.com/drugs/DB13878ApprovedInvestigationalMavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with regimens either containing an NS5A inhibitor or an NS3/4A protease inhibitor, but not both [L940]. … Pibrentasvir is available as an oral combination therapy with [DB13879] under the brand name Mavyret.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesAntipyrine
go.drugbank.com/drugs/DB01435ApprovedAn analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesBismuth subnitrate
go.drugbank.com/drugs/DB13209ApprovedWithdrawnThe use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Human thrombin
go.drugbank.com/drugs/DB11571ApprovedInvestigationalHuman thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting.
Mixtures: EVICEL® SELLANTE DE FIBRINA HUMANA, EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/mlPenicillium chrysogenum var. chrysogenum
go.drugbank.com/drugs/DB10439ApprovedPenicillium chrysogenum var. chrysogenum is a fungus which can provoke allergic reactions. Penicillium chrysogenum var. chrysogenum extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold Mixture