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Linaprazan
go.drugbank.com/drugs/DB20602InvestigationalThe usage of the INN stem '-prazan' in the name indicates that Linaprazan is a proton pump inhibitor, not dependent on acid activation.
Prusogliptin
go.drugbank.com/drugs/DB20606InvestigationalThe usage of the INN stem '-gliptin' in the name indicates that Prusogliptin is a dipeptidyl aminopeptidase-IV inhibitor.
Amsilarotene
go.drugbank.com/drugs/DB21085InvestigationalThe usage of the INN stem '-arotene' in the name indicates that Amsilarotene is a arotinoid derivative.
Ocedurenone
go.drugbank.com/drugs/DB21519InvestigationalThe usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.
Brimarafenib
go.drugbank.com/drugs/DB21706InvestigationalThe usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.
XC221
go.drugbank.com/drugs/DB16503InvestigationalXC221 was investigated in clinical trials to treat patients with respiratory infections, including influenza, COVID-19, and other acute viral upper respiratory infections.
Contusugene ladenovec
go.drugbank.com/drugs/DB05322InvestigationalINGN 201(Advexin) is a replication-impaired adenoviral vector that carries the p53 gene, has been evaluated in both preclinical and clinical trials.
FRAX716
go.drugbank.com/drugs/DB31795ExperimentalFRAX716 is a group I-specific p21-activated kinase (PAK) inhibitor which dramatically inhibits the phosphorylation of PAK and Mek1.[A274678]
CIGB-258 peptide
go.drugbank.com/drugs/DB15809ExperimentalAs of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens … CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant.
Alteminostat
go.drugbank.com/drugs/DB19620InvestigationalThe usage of the INN stem '-inostat' in the name indicates that Alteminostat is a histone deacetylase inhibitor.