Linaprazan

DB20602InvestigationalSmall molecule

Linaprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Linaprazan is a proton pump inhibitor, not dependent on acid activation. Linaprazan... Linaprazan is under investigation in clinical trial NCT00206284 (A Dose-finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis.).

Chemical structure of Linaprazan
Formula / weight
C21H26N4O2 · 366.465 g/mol (avg)
Code names
AZD-0865

Resolves to

Compound
UNIIE0OU4SC8DPCAS248919-64-4ChEMBLCHEMBL497011ChEBI748987PubChem9951066
Structure
InChIKeyGHVIMBCFLRTFHI-UHFFFAOYSA-NSMILESCC1=C(C)N2C=C(C=C(NCC3=C(C)C=CC=C3C)C2=N1)C(=O)NCCO
Targets
P20648ATP4AP51164ATP4B

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2Clinical trialsPhase, status and sponsor resolved per trial
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Linaprazan, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In