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IO-202
go.drugbank.com/drugs/DB17548InvestigationalIO-202 is a first-in-class antibody targeting the Leukocyte Immunoglobulin-Like Receptor subfamily B (LILRB) member 4 (LILRB4).[A257276] It is being investigated in cancers.
Lysergic acid 2,4-dimethylazetidide
go.drugbank.com/drugs/DB15196ExperimentalLysergic acid 2,4-dimethylazetidide is under investigation in clinical trial NCT02765802 (A Study to Evaluate Pegylated Interferon Lambda Monotherapy in Patients With Chronic Hepatitis Delta Virus Infection
Zetomipzomib
go.drugbank.com/drugs/DB16070InvestigationalZetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).
Synonyms: (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamidehumanized SMART Anti-IL-12 Antibody
go.drugbank.com/drugs/DB05848ExperimentalThe humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La Roche Inc
Bacillus calmette-guerin substrain tokyo 172-1 live antigen
go.drugbank.com/drugs/DB14968InvestigationalBacillus calmette-guerin substrain tokyo 172-1 live antigen is under investigation in clinical trial NCT03091660 (S1602: Different Strains of BCG With or Without Vaccine in High Grade Non- Muscle Invasive
AVXS-301
go.drugbank.com/drugs/DB17943ExperimentalAVXS-301 consists of an adeno-associated virus serotype 9 (AAV9) designed to express the superoxide dismutase 1 (SOD1) gene.
Rocapuldencel-T
go.drugbank.com/drugs/DB17588InvestigationalRocapuldencel-T is an autologous dendritic cell immunotherapy that was investigated in NCT02662634 (A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer
SPVN20
go.drugbank.com/drugs/DB33936ExperimentalSPVN20 is under investigation in clinical trial NCT07807111 (Open-Label Study to Evaluate the Safety, Tolerability, and Efficacy of Gene Therapy (SPVN20) in Subjects With Rod-Cone Dystrophy).
Deudextromethorphan
go.drugbank.com/drugs/DB19054Investigationalunder investigation in clinical trial NCT02153502 (Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to
Gumelutamide
go.drugbank.com/drugs/DB21615ExperimentalThe usage of the INN stem '-lutamide' in the name indicates that Gumelutamide is a non-steroid antiandrogen. Gumelutamide has a monoisotopic molecular weight of 420.15 Da.