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Petrelintide
go.drugbank.com/drugs/DB19442InvestigationalPetrelintide is under investigation in clinical trial NCT06662539 (Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities).
Synonyms: 3,8-anhydro[N-(19-carboxynonadecanoyl)- L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L -lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-(2S)-α-2-aminoadipyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-arginyl, L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-γ-glutamyl-L-arginyl-L-α-aspartylglycyl-L-threonyl-L-alanyl-L-threonyl-L-lysyl-L-alanyl-L-threonyl-L-α-glutamyl-L-arginyl-L-leucyl-L-alanyl-5-carboxy-L-norvalyl-L-phenylalanyl-L-leucyl-L-glutaminyl-L-argiRaludotatug deruxtecan
go.drugbank.com/drugs/DB19447InvestigationalRaludotatug deruxtecan is under investigation in clinical trial NCT06660654 (A Study of Raludotatug Deruxtecan in Participants With Advanced/metastatic Solid Tumors (Rejoice-pantumor01)).
Synonyms: R-DXd, immunoglobulin G1-kappa, anti-[Homo sapiens CDH6(cadherin 6, K-cadherin (foetal kidney), cadherin 6 type 2)], humanized monoclonal antibody conjugated to deruxtecan, comprising a linker and a camptothecinDorocubicel
go.drugbank.com/drugs/DB19448Approvedfollowing myeloablative conditioning in adult patients for whom a suitable donor is not available. … Dorocubicel is a preparation of cryopreserved allogeneic umbilical cord-derived hematopoietic stem cells and blood progenitors expanded _ex vivo_ using [UM-171].
TDI-01
go.drugbank.com/drugs/DB19450InvestigationalTDI-01 is a small molecule is being developed by Beijing Tide Pharmaceutical.
MIP-1095 I-131
go.drugbank.com/drugs/DB14978InvestigationalMIP-1095 I-131 is under investigation in clinical trial NCT03030885 (Use of an Experimental Radiopharmaceutical (131I-MIP-1095) in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)).
Martinostat
go.drugbank.com/drugs/DB14979InvestigationalMartinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
Nomacopan
go.drugbank.com/drugs/DB14991InvestigationalNomacopan is under investigation in clinical trial NCT03427060 (Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms).
Categories: Recombinant Protein Inhibitor of Complement Factor 5Pegunigalsidase alfa
go.drugbank.com/drugs/DB14992ApprovedInvestigationalPegunigalsidase alfa (PRX-102) is a recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease, a rare genetic disorder characterized … to a different glycosylation pattern.
Pateclizumab
go.drugbank.com/drugs/DB14997InvestigationalPateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared … With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis).
Human interferon beta
go.drugbank.com/drugs/DB14999ApprovedInvestigational[A191784] Interferon beta is currently being studied as a possible treatment for COVID-19, which results from infection with the novel 2019 SARS-CoV-2 virus. … It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity.[A191733,L12012]
Categories: Interferon Type I