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OTX-2002
go.drugbank.com/drugs/DB17246InvestigationalOTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins, encapsulated in a lipid nanoparticle (LNP).
BNT111
go.drugbank.com/drugs/DB18177InvestigationalBNT111 is an investigational cancer immunotherapy under development for advanced melanoma. It consists of a fixed combination of mRNA-encoded, tumor-associated antigens.
alpha-Hydroxylinoleic acid
go.drugbank.com/drugs/DB16027Investigationalalpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).
Ribaxamase
go.drugbank.com/drugs/DB16311InvestigationalRibaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Aviscumine
go.drugbank.com/drugs/DB12684InvestigationalCy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).
Tomligisiran
go.drugbank.com/drugs/DB19330InvestigationalTomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis
Synonyms: AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN-9-YL))DA), 3'-(O-Daplusiran
go.drugbank.com/drugs/DB19331InvestigationalDaplusiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis
Nomegestrol
go.drugbank.com/drugs/DB11636ApprovedNomegestrol is an ingredient in the EMA-authorised product Zoely.
Categories: Hormonal Contraceptives for Systemic Use1-benzylimidazole
go.drugbank.com/drugs/DB04581Experimental1-benzylimidazole, an N-imidazole derivative, has been shown to have strong cardiotonic activity.
ARCT-810
go.drugbank.com/drugs/DB17683InvestigationalARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes.