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Pilaralisib
go.drugbank.com/drugs/DB11772InvestigationalPilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K). … Pilaralisib has been used in trials studying the treatment of Cancer, Lymphoma, Solid Tumors, Glioblastoma, and Breast Cancer, among others.
Kava
go.drugbank.com/drugs/DB01322ApprovedInvestigationalNutraceuticalWithdrawnCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesTioxolone
go.drugbank.com/drugs/DB13343ExperimentalCategories: Anti-Acne Preparations for Topical UseDesoxycortone
go.drugbank.com/drugs/DB15972ExperimentalCategories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainEpicillin
go.drugbank.com/drugs/DB13300ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseCEP-1347
go.drugbank.com/drugs/DB05403InvestigationalCEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons
Dihematoporphyrin ether
go.drugbank.com/drugs/DB15351InvestigationalDihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma).
Categories: Heterocyclic Compounds with 4 or More RingsMYR-101
go.drugbank.com/drugs/DB17075InvestigationalIt is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase enzyme (ASPA). … Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain.
KOS-1584
go.drugbank.com/drugs/DB05903InvestigationalKOS-1584 is a second-generation epothilone. Epothilones are anticancer agents with a taxane-like mechanism of action that have demonstrated activity in taxane-resistant tumors. … KOS-1584 is a second-generation compound with increased potency, favorable tissue distribution, and ease of formulation.
Synonyms: (E)-9,10-Dehydroepothilone D, (E)-9,10-Didehydroepothilone D