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LX-7101
go.drugbank.com/drugs/DB16009InvestigationalLX-7101 is under investigation in clinical trial NCT01528111 (Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension).
PF-06882961
go.drugbank.com/drugs/DB16043InvestigationalPF-06882961 is under investigation in clinical trial NCT03985293 (A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus).
AIM-102
go.drugbank.com/drugs/DB16176InvestigationalAIM-102 is under investigation in clinical trial NCT01501942 (Efficacy, Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Oral Administration of AIM-102 in Patients With Mild to Moderate Allergic
PF-06291874
go.drugbank.com/drugs/DB15065InvestigationalPF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes
YF087
go.drugbank.com/drugs/DB33921ExperimentalYF087 is under investigation in clinical trial NCT07809607 (A Study to Evaluate YF087 in Subjects With MSI-H or dMMR Advanced Solid Tumors).
WX-554
go.drugbank.com/drugs/DB21749InvestigationalWX-554 is under investigation in clinical trial NCT01581060 (Phase I/II Dose-escalation Study to Investigate Safety and Pharmacokinetics/ Pharmacodynamics of WX-554 in Patients With Solid Tumours).
Urolithin A
go.drugbank.com/drugs/DB15464ExperimentalIt has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.[A179494]
KAI-1455
go.drugbank.com/drugs/DB06064ExperimentalIn preclinical studies, KAI-1455 showed a dramatic reduction in infarct size when delivered prior to the ischemic insult. … KAI-1455 is a selective epsilon protein kinase C (εPKC) activator designed to reduce ischemic organ injury during procedures where blood supply may be compromised, such as coronary artery bypass grafting
Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle (VLP) vaccine
go.drugbank.com/drugs/DB16431ExperimentalRegarding this vaccine specifically, it stimulates the immune system to produce anti-receptor binding domain antibodies[A226593]. … Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV-2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated to
Saralasin
go.drugbank.com/drugs/DB06763ExperimentalCategories: Agents Acting on the Renin-Angiotensin System