Urolithin A

DB15464ExperimentalSmall molecule

Urolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.

Mechanism: Pharmacologically active on Aryl hydrocarbon receptor and Nuclear factor erythroid 2-related factor 2
Curator reviewed
Formula / weight: C₁₃H₈O₄ · 228.2002 g/mol (avg)
Also known as: 3,8-Dihydroxyurolithin · Uro-A · UroA

Resolves to

Compound

UNIIILJ8NEF6DTCAS1143-70-0ChEMBLCHEMBL1836264ChEBI168442PubChem5488186

Clinical / RWD

RxNorm612018

Structure

InChIKeyRIUPLDUFZCXCHM-UHFFFAOYSA-NSMILESOC1=CC2=C(C=C1)C1=C(C=C(O)C=C1)C(=O)O2

Targets

P35869AHRQ16236NFE2L2

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Urolithin A, and which of those have an active Phase 3 trial?

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