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Displaying results 6981 - 6990 of 10000 in total
  1. Drug

    ADU-S100

    go.drugbank.com/drugs/DB14722
    Investigational

    ADU-S100 (MIW815) is a synthetic cyclic dinucleotide (CDN) agonist (activator) of Stimulator of Interferon Genes (STING), a receptor crucial to activate the innate (endogenous) immune system. … ADU-S100 (MIW815) activates all known human and mouse STINGs, and effectively induces the expression of cytokines and chemokines, leading to a robust and durable antigen-specific T-cell mediated immune

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  2. Drug

    3-Allylfentanyl

    go.drugbank.com/drugs/DB09169
    ExperimentalIllicit

    3-allyfentanyl is a fentanyl derivative opioid that can cause itching, nausea and serious respiratory depression. … Fentanyl and its analogs have killed thousands of people around the world as drugs of abuse.

  3. Drug

    Quisqualic acid

    go.drugbank.com/drugs/DB02999
    Experimental

    Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium … The compound is obtained from the seeds and fruit of _Quisqualis chinensis_.

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    Mirococept

    go.drugbank.com/drugs/DB06492
    Experimental

    Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. … It consists of the first three short consensus domains of human complement receptor 1 (CR1), manufactured in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the

    Synonyms: myristoylated recombinant SCR1-3 of human complement reseptor type I
  5. Drug

    Distearyldimonium

    go.drugbank.com/drugs/DB14143
    ApprovedWithdrawn

    Synonyms: Dioctadecyldimethylammonium ionCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    PHE885

    go.drugbank.com/drugs/DB18123
    Investigational

    PHE885 is an investigational, autologous B-cell Maturation Antigen (BCMA)-directed chimeric antigen receptor (CAR)-T cell therapy.

  7. Drug

    Cepeginterferon alfa-2B

    go.drugbank.com/drugs/DB12814
    Investigational

    Cepeginterferon alfa-2B is under investigation in clinical trial NCT01889433 (An Open-label Comparative Efficacy and Safety Study of Algeron (Cepeginterferon Alfa-2b) in Treatment-naive Patients With Chronic

    Categories: Antineoplastic and Immunomodulating Agents
  8. Drug

    RDEA806

    go.drugbank.com/drugs/DB05228
    Investigational

    RDEA806 is a new HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with a high genetic barrier to resistance and a broad spectrum of activity.

  9. Drug

    Ozone

    go.drugbank.com/drugs/DB12510
    Investigational

    Ozone has been used in trials studying the treatment of Mild Asthma and Primary Apical Periodontite.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. … Due to these differences, this drug is classified as a nonbenzodiazepine anxiolytic.