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Displaying results 61 - 70 of 152092 in total
  1. Drug

    Talquetamab

    go.drugbank.com/drugs/DB16678
    ApprovedInvestigational

    [L47765] Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and CD3 on T cells. … It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: ANTIBODY; BISPECIFIC GAMMA4 HEAVY CHAIN HUMANIZED AN, IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL
  2. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. … for cleaving large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 is responsible for the microangiopathic complications associated with cTTP

    Categories: Amino Acids, Peptides, and Proteins, Enzymes and CoenzymesSynonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs
  3. Drug

    Obecabtagene autoleucel

    go.drugbank.com/drugs/DB17362
    ApprovedInvestigational

    [L52450] Obecabtagene autoleucel was also investigated in other hematological cancers and systemic lupus erythematosus.[A265045] … Obecabtagene autoleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy with a fast off-rate binding profile for CD19.

    Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsSynonyms: PACKAGING SIGNAL (.PSI.), THE REV RESPONSIVE ELEMENT (RRE) AND THE CENTRAL POLYPURINE TRACT (CPPT) ARE RETAIN, SELF-INACTIVATING LENTIVIRAL VECTOR CONSISTING OF 5' FUSION BETWEEN THE CMV PROMOTER AND HIV LTR, WHERE THE CMV PROMOTER REPLACES THE U3 REGION.
  4. Drug

    Undecylenic acid

    go.drugbank.com/drugs/DB11117
    Approved

    It serves as an acid moiety for anabolic steroid boldenone. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.

    Synonyms: Undecenoic acid, 10-undecenoic acidMixtures: Foot and Body Powder, Fungi Nail Toe and Foot MS
  5. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).

    Mixtures: HalfLytely and Bisacodyl, HalfLytely and BisacodylCategories: Alimentary Tract and Metabolism, Phenols
  6. Drug

    Aluminum cation

    go.drugbank.com/drugs/DB14519
    Experimental

    Synonyms: Aluminum(3+), Aluminum(III)
  7. Drug

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

    go.drugbank.com/drugs/DB18681
    Experimental

    Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. … It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.

    Synonyms: Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase
  8. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. … Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes.

    Synonyms: 2-Acetoxybenzoic acid, acetyl salicylic acidInternational brands: Solprin acid
  9. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. … For example, folic acid is present in green vegetables, beans, avocado, and some fruits.

    Synonyms: N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid, Folic acidMixtures: Sodium polysulthionate and folic acid, Sodium Polysulthionate and Folic Acid
  10. Drug

    Glycolic acid

    go.drugbank.com/drugs/DB03085
    Approved

    Mixtures: Skin White Pro Strength Kojic and Hyaluronic Skin Lightening Serum, GLYCOLIC Acid 50 BUFFERED Skin Chemical PeelCategories: Acids, Acyclic, Hydroxy Acids