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Displaying results 61 - 70 of 10818 in total
  1. Drug

    Atidarsagene autotemcel

    go.drugbank.com/drugs/DB17538
    ApprovedInvestigational

    Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic

    Synonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) geneCategories: Autologous Hematopoietic Stem Cell-Based Gene Therapy, Enzymes and Coenzymes
  2. Drug

    Sage oil

    go.drugbank.com/drugs/DB11199
    ApprovedNutraceutical

    *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and perennial plants with flowers. … Essential oil has been traditionally used in medicine for the relief of pain and the treatment of inflammation and infections, as it is reported to exhibit carminative, antispasmodic, antiseptic, and astringent

    Synonyms: Salvia officinalis leaf oil, Salvia officinalis (sage) oil
  3. Drug

    Hawthorn leaf with flower

    go.drugbank.com/drugs/DB15839
    Investigational

    Synonyms: Flowering top component of crataegus
  4. Drug

    Medical Cannabis

    go.drugbank.com/drugs/DB14009
    Investigational

    to contain different concentrations of CBD and THC. … Due to the differences in receptor profile between CBD and THC, these cannabinoids are understandably used to treat different conditions.

    Synonyms: Hashish top, Marijuana top
  5. Drug

    Placental Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15730
    Investigational

    It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells. … The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs).

    Synonyms: Placental Mesenchymal Stem Cells
  6. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA.

    Synonyms: Human t-PA (residues 1-3 and 176-527)Categories: Enzymes and Coenzymes, Blood and Blood Forming Organs
  7. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery. … It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label]. It is a weaker laxative than bisacodyl or castor oil[A177092].

    Salts: Sennosides A and BMixtures: Senna and Docusate Sodium, Senna and Docusate Sodium
  8. Drug

    Penicillium glaucum

    go.drugbank.com/drugs/DB14171
    Approved

    Penicillium glaucum allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, penicillium glaucum, Molds, rusts and smuts, penicillium glaucus
  9. Drug

    VOR33

    go.drugbank.com/drugs/DB18624
    Investigational

    VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.

    Synonyms: allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein
  10. Drug

    Althea root

    go.drugbank.com/drugs/DB13525
    Experimental

    Synonyms: Althaea officinalis rootCategories: Cough and Cold Preparations