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Atidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigationalAtidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) geneElapegademase
go.drugbank.com/drugs/DB14712Approvedgroup in alanine and lysine residues. … [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on October 5, 2018.[L4654,F1939]
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH, AN AVERAGE OFAPPROXIMATELY 13 .OMEGA.MM-111
go.drugbank.com/drugs/DB17983InvestigationalMM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Antibody bispecific for erbb2 and erbb3Romilkimab
go.drugbank.com/drugs/DB16318InvestigationalRomilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)Radotermin
go.drugbank.com/drugs/DB19127InvestigationalRadotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the
Synonyms: Recombinant human growth and differentiation factor-5Factor IX Complex (Human)
go.drugbank.com/drugs/DB11330ApprovedInvestigationalCoagulation factors are purified from pooled human plasma and subsequently sterilized and treated. … For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) contains heparin.
Synonyms: Coagulation factor IX, II, VII and X in combinationCategories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsMucor circinelloides f. circinelloides
go.drugbank.com/drugs/DB15512ApprovedMucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, mucor circinelloides f. circinelloidesFluorescein
go.drugbank.com/drugs/DB00693ApprovedInvestigationalinjuries and corneal trauma. … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal
Mixtures: Minims Lidocaine and Fluorescein, Fluorescein Sodium and Proparacaine HydrochlorideCategories: Indicators and ReagentsNogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigational[A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which … [L50627] Non-muscle invasive bladder cancer (NMIBC), which accounts for 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsSynonyms: Fusion protein consisting of il-15n72d and il-15rasu/fcGoflikicept
go.drugbank.com/drugs/DB16396InvestigationalGoflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein