Search

Displaying results 61 - 70 of 91 in total
  1. Drug

    AGIL-FA

    go.drugbank.com/drugs/DB16973
    Experimental

    Synonyms: Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein
  2. Drug

    AAV2/8.TBG.hARSB

    go.drugbank.com/drugs/DB17633
    Investigational

    Synonyms: Adeno-associated viral vector serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter driving the expression of the human ARSB gene
  3. Drug

    Elivaldogene tavalentivec

    go.drugbank.com/drugs/DB19095
    Investigational

    Synonyms: Dna (lentiviral vector clone lenti-d human x-linked adrenoleukodystrophy abcd1 gene cdna-specifying), A vsv-g*-pseudotyped self-inactivating hiv-1-derived lentiviral vector (plbp100 hald) encoding human adrenoleukodystrophy (ald) protein (abcd1 gene) under the control of a modified myeloproliferative sarcoma
  4. Drug

    OTL-102

    go.drugbank.com/drugs/DB18642
    Experimental

    OTL-102 consists of autologous CD34+ enriched cells that contain hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene.

    Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human gp91phox gene
  5. Drug

    OTL-203

    go.drugbank.com/drugs/DB18643
    Investigational

    OTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.

    Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene
  6. Drug

    CAM-GM201

    go.drugbank.com/drugs/DB17687
    Experimental

    Synonyms: Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta subunits
  7. Drug

    Revakinagene taroretcel

    go.drugbank.com/drugs/DB05344
    ApprovedInvestigational

    Revakinagene taroretcel is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is an allogeneic encapsulated cell-based gene therapy that contains 200,000...

    Synonyms: allogenic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth factor
  8. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

    Categories: Adeno-associated Viral Vector TherapiesSynonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)
  9. Drug

    Delolimogene mupadenorepvec

    go.drugbank.com/drugs/DB17326
    Investigational

    Synonyms: Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound isoleucine zipper-containing human cd40 ligand-specifying)
  10. Drug

    RP-A501

    go.drugbank.com/drugs/DB17647
    Investigational

    RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is bein...

    Synonyms: Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein 2 isoform B transgene (AAV9.LAMP2B)