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Displaying results 691 - 700 of 10000 in total
  1. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    [A262681] It was granted approval by Health Canada in September 2010.[L49206] … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008.

    Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: LASOMID IN, BENVIDA 10 MG/ML IV INFUZYON COZELTISI, 20 ML
  2. Drug

    Alteplase

    go.drugbank.com/drugs/DB00009
    ApprovedInvestigational

    [A252330,L43125] Alteplase is a purified glycoprotein of 527 amino acids expressed in Chinese hamster ovary (CHO) cells. … Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots.

    Products: Activase RT-PA Inj
  3. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper … Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of _Streptomyces caespitosus_.

    Categories: Compounds used in a research, industrial, or household settingProducts: Mutamycin Inj 5mg/vial, Mutamycin Inj 20mg/vial
  4. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.

    Products: Codeine Phosphate Inj 30mg/ml, Codeine Phosphate Inj 60mg/ml
  5. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … [A231204] Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis.

    Products: Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen, Ketotifen Stulln 250 Mikrogramm/ml Augentropfen im Einzeldosisbehältnis
  6. Drug

    Sodium iodide

    go.drugbank.com/drugs/DB11119
    ApprovedInvestigational

    Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine. … Sodium iodide is a water-soluble ionic compound with a crystal lattice.

    Products: Micro I, Sodium Iodide Inj 100mg/ml
  7. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use. … Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced

    Products: LUCRIN DEPOT-3,75 MG IM/SC ENJEKSIYONLUK FLAKON, 1 ADET, LUCRIN DEPOT-3 M 11,25 IM/SC ENJEKSIYONLUK FLAKON, 1 ADET
  8. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    into therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced

    Products: Isoptin Inj 2.5mg/ml, ISOPTIN IV INFUZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 ADET
  9. Drug

    Colistin

    go.drugbank.com/drugs/DB00803
    ApprovedInvestigational

    It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

    Products: Rican Premix Powder 1,900 IU/mg, Collis Colistin 1,500,000 IU/g Water Soluble Powder
  10. Indication

    Relapsed Multiple Myeloma

    go.drugbank.com/conditions/DBCOND0031510
    Drugs: Belantamab mafodotin · Carfilzomib · Ciltacabtagene autoleucel · Daratumumab · Dexamethasone · Elranatamab +8 more
    Synonyms: Multiple Myeloma in Relapse