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Displaying results 6991 - 7000 of 10000 in total
  1. Drug

    Inlexisertib

    go.drugbank.com/drugs/DB21713
    Investigational

    Inlexisertib is under investigation in clinical trial NCT05957367 (A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies). … Inlexisertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Inlexisertib is a serine/threonine kinase inhibitor.

  2. Drug

    Fenspiride

    go.drugbank.com/drugs/DB08979
    Investigational

    Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. … It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis

  3. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)). … It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671]

    Synonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)
  4. Drug

    AV-COVID-19

    go.drugbank.com/drugs/DB15802
    Investigational

    The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration. … The vaccine was developed and tested by Aivita Biomedical, Inc.. As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.

  5. Drug

    Inetetamab

    go.drugbank.com/drugs/DB17457
    Investigational

    Inetetamab is a trastuzumab analog. It differs from trastuzumab by a two amino acid variation in its Fc domain (allotype variation), and possesses an exact F(ab’)2 of trastuzumab.

  6. Drug

    Melarsomine

    go.drugbank.com/drugs/DB11528
    ExperimentalVet approved

    It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection. … Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide.

  7. Drug

    Mesterolone

    go.drugbank.com/drugs/DB13587
    Investigational

    It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. … Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT).

  8. Drug

    Sulfaisodimidine

    go.drugbank.com/drugs/DB13283
    Experimental

    Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has been

  9. Drug

    Viquidacin

    go.drugbank.com/drugs/DB19549
    Experimental

    Viquidacin is a small molecule drug. The usage of the INN stem '-dacin' in the name indicates that Viquidacin is a antibiotic, DNA gyrase and topoisomerase IV inhibitor.

  10. Drug

    Abitesartan

    go.drugbank.com/drugs/DB19863
    Experimental

    Abitesartan is a small molecule drug. The usage of the INN stem '-sartan' in the name indicates that Abitesartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic).