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Sirpiglenastat
go.drugbank.com/drugs/DB17536InvestigationalIt is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors). … Sirpiglenastat, also known as DRP-104, is a prodrug of [6-diazo-5-oxo-L-norleucine] (DON), which is a broad-acting glutamine antagonist.
Synonyms: L-norleucine, n-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl ester, Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoateBosakitug
go.drugbank.com/drugs/DB19101InvestigationalBosakitug (BSI-045B) is under investigation in clinical trial NCT05932654 (POC Study to Evaluate BSI-045B Monotherapy and BSI-045B Add-on Therapy With Dupilumab in Atopic Dermatitis).
D-glyceraldehyde 3-phosphate
go.drugbank.com/drugs/DB02263ExperimentalAn aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.
gamma-Aminobutyric acid
go.drugbank.com/drugs/DB02530ApprovedInvestigationalThe most common inhibitory neurotransmitter in the central nervous system.
Synonyms: γ-amino-n-butyric acidProducts: Gongjinhyang Qi and Jin EyeVirginiamycin
go.drugbank.com/drugs/DB11476ExperimentalVet approvedVirginiamycin is used in the fuel ethanol industry to prevent microbial contamination and in livestock to prevent and treat infections. … According to a USDA study, antibiotics can save as much as 30% in feed costs among young swine.
Conteltinib
go.drugbank.com/drugs/DB21262InvestigationalConteltinib is under investigation in clinical trial NCT06970132 (Study of SY-5933 Plus CT-707 in Advanced Solid Tumors With KRAS p.G12C Mutation). … Conteltinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Conteltinib is a tyrosine kinase inhibitor.
Osunprotafib
go.drugbank.com/drugs/DB21547InvestigationalOsunprotafib is under investigation in clinical trial NCT04777994 (Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors). … Osunprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Osunprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor.
Zoracopan
go.drugbank.com/drugs/DB21702InvestigationalZoracopan is under investigation in clinical trial NCT06173596 (A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults). … Zoracopan is a small molecule drug. The usage of the INN stem '-copan' in the name indicates that Zoracopan is a complement receptor antagonist/complement inhibitor.
Mesoheme
go.drugbank.com/drugs/DB02577ExperimentalIt is found free in tissues and as the prosthetic group in many hemeproteins.