Search
Lornoxicam
go.drugbank.com/drugs/DB06725ApprovedInvestigationalLornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of...
Mixtures: LORNOPAR 8/300 MG EFERVESAN TABLET ,20 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesPirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigational[A251365] The FDA first approved pirfenidone alongside [nintedanib] as one of the first drugs to treat IPF.[A251165] … [A251370] While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and modulate cellular oxidation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: PİRFA 600 MG FİLM KAPLI TABLET, 120 ADET, PİRFA 400 MG FİLM KAPLI TABLET, 180 ADETPheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … Pheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as [cetirizine] and [loratadine].
Mixtures: ANTIBEKSIN SURUP, 100 ML, Top Care Flu and Sore ThroatProducts: FENAMED 45,5 MG/2 ML IM/IV ENJ. COZ. ICEREN 50 AMPUL, INFENIL 45.5 MG/2 ML IM/IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,50 AMPULSecukinumab
go.drugbank.com/drugs/DB09029ApprovedInvestigational[L39600] By blocking the actions of IL-17A, secukinumab works to inhibit the pro-inflammatory pathways that drive immune-mediated inflammatory disorders. … [A249805] It is currently approved to treat a number of chronic inflammatory conditions, such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and hidradenitis suppurativa.
Products: VERXANT 150 MG SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET, VERXANT 150 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADETIrbesartan
go.drugbank.com/drugs/DB01029ApprovedInvestigationalIrbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy. … [L7456,L7459] It can also be used as part of a combination product with [hydrochlorothiazide] for patients not well controlled or not expected to be well controlled on monotherapy.
Mixtures: İRDAPİN 150 MG/10 MG FİLM KAPLI TABLET, 28 ADET, KARVEA DUO 150 MG / 10 MG FILM KAPLI TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsBupivacaine
go.drugbank.com/drugs/DB00297ApprovedInvestigationalBupivacaine is a widely used local anesthetic agent.
Mixtures: BUPITROY® HEAVY 5 MG/ML, BUVACAINA® PESADA SOLUCION INYECTABLE 20 MG/ 4 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCalcium glubionate anhydrous
go.drugbank.com/drugs/DB13142ApprovedCalcium glubionate (or glubionate calcium) is a mineral supplement to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets.
Products: CALCIUM SANDOZ 10 ML 1,375 GR AMPUL, 5 ADET, CALCIUM SANDOZ %10 AMPUL, 50 ADETCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalCitalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]
Mixtures: Sentralopram AM-10Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsRofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%. … Cytochrome P450 1A2, Cytochrome P450 3A4, Cytochrome P450 2C9, Cytochrome P450 2C8, and Prostaglandin G/H synthase 1 are known to metabolize rofecoxib.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanoneEplerenone
go.drugbank.com/drugs/DB00700ApprovedInvestigationalEplerenone selectively binds to recombinant human mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and androgen receptors. … Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EPLEDAY 50 MG FILM KAPLI TABLET, 100 ADET, EPLEDAY 25 MG FILM KAPLI TABLET, 100 ADET