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Displaying results 701 - 710 of 5896 in total
  1. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    Factor IX (FIX) deficiency) who are negative for neutralizing antibodies to variant AAV serotype Rh74. … from week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period.

  2. Drug

    Olsalazine

    go.drugbank.com/drugs/DB01250
    Approved

    [A257063] It was first developed for delivering mesalamine to the colon without the use of [sulfapyridine]. … [A257078] Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.

  3. Drug

    Letermovir

    go.drugbank.com/drugs/DB12070
    ApprovedInvestigational

    Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives ca...

  4. Drug

    Aripiprazole

    go.drugbank.com/drugs/DB01238
    ApprovedInvestigational

    Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation ...

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ARIPIPRAZOLO DOC GENERICI, ARIPIPRAZOLO MYLAN GENERICS
  5. Drug

    Pheniramine

    go.drugbank.com/drugs/DB01620
    Approved

    Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine].

    Mixtures: Care One Flu and Sore Throat
  6. Drug

    Adapalene

    go.drugbank.com/drugs/DB00210
    ApprovedInvestigational

    treat mild-to-severe acne. … [A193518] Adapalene has similar efficacy but a superior safety profile compared to tretinoin.

    Products: DIFACLEAR GEL 0.1%w/w, DIFACLEAR GEL 0.1% W/W
  7. Drug

    Cystine

    go.drugbank.com/drugs/DB00138
    ApprovedInvestigationalNutraceuticalWithdrawn

    Two molecules of cysteine are joined together by a disulfide bridge to form cystine.

  8. Drug

    Efalizumab

    go.drugbank.com/drugs/DB00095
    ApprovedWithdrawn

    Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. … It was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797]

  9. Drug

    Vildagliptin

    go.drugbank.com/drugs/DB04876
    ApprovedInvestigational

    [L32803] Vildagliptin is also available as Eucreas, a fixed-dose formulation with metformin for adults in who do not adequately glycemic control from monotherapy. … It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired.

    Products: MIU TWO
  10. Drug

    Mifepristone

    go.drugbank.com/drugs/DB00834
    ApprovedInvestigational

    As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome. … The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg). Currently under investigation for use in psychotic depression (phase 3 trials).