DB00138ApprovedInvestigationalNutraceuticalWithdrawnSmall molecule
Cystine is an oxidated derivative of the amino acid cysteine found in various nutritional products, acne treatments, and creams to treat cervical injury or inflammation. A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine.
- Mechanism
- Curator reviewed
Certain conditions, e.g. an acetaminophen overdose, deplete hepatic glutathione and subject the tissues to oxidative stress resulting in loss of cellular integrity. L-Cystine serves as a major precursor for synthesis of glutathione.
- Primary indication
- It has been claimed that L-cysteine has anti-inflammatory properties, that it can protect against various toxins, and that it might be helpful in osteoarthritis and rheumatoid arthritis.Curator reviewed · 8 structured indications
- Formula / weight
- C6H12N2O4S2 · 240.3 g/mol (avg)
- First approval
- Canada, 2005
- Also known as
- L-Cystine · L-Dicysteine
Resolves to
Clinical / RWD
Structure
InChIKey
LEVWYRKDKASIDU-IMJSIDKUSA-NSMILESN[C@@H](CSSC[C@H](N)C(O)=O)C(O)=OTargets
Transporters
What you can answer from here — as of September 23, 2026
2Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
3TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Cystine, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account