Search
Ranitidine
go.drugbank.com/drugs/DB00863ApprovedWithdrawn[L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine].
Products: RANIDURA T 150MG, RANIDURA T 300MGTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigational[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeGlycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: Clinimix E, Clinimix EProducts: GLICINA 1.5% SOLUCION DE IRRIGACIONIloperidone
go.drugbank.com/drugs/DB04946ApprovedInvestigational[A3024] It is considered to be a second-generation antipsychotic drug [A263552] with multiple receptor binding profile, although it shows high affinity towards 5-HT<sub>2A</sub> and dopamine D2 receptors … Iloperidone is a benzisoxazole [A263557] and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnIt also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.
Products: PIPERACILLINA E TAZOBACTAM EG, TETRACICLINA DE 500 MG CAPSULASDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnAccording to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. … (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942]
Categories: Sex Hormones and Modulators of the Genital SystemSynonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexene, α,α'-diethyl-(E)-4,4'-stilbenediolCisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnThe FDA issued a warning letter regarding this risk to health care professionals and patients. … In many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeTecovirimat
go.drugbank.com/drugs/DB12020ApprovedInvestigational[A35131,A35143] Tecovirimat was approved by the FDA in July 2018 as the first drug ever approved to treat smallpox. … [L40159] Other than smallpox, tecovirimat is also indicated to treat complications due to replication of the vaccinia virus following vaccination against smallpox, and to treat monkeypox and cowpox in
Thyroglobulin
go.drugbank.com/drugs/DB01584ApprovedWithdrawnThyroglobulin (also known as Tg) is an enzyme thyroid hormone used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). … The active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase.
Pergolide
go.drugbank.com/drugs/DB01186ApprovedVet approvedWithdrawnThe drug was withdrawn from the US market in March 2007 and from the Canadian market in August 2007. … It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome. It was later found that pergolide increased the risk of cardiac valvulopathy.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome