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Izumerogant
go.drugbank.com/drugs/DB21604ExperimentalIzumerogant is a small molecule drug. … The usage of the INN stem '-rogant' in the name indicates that Izumerogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist.
Glovadalen
go.drugbank.com/drugs/DB21709InvestigationalGlovadalen is a small molecule drug. … Glovadalen is under investigation in clinical trial NCT06970301 (A Study to Assess the Safety and Tolerability, and Pharmacokinetics of UCB0022 in Healthy Caucasian, Japanese, and Chinese Participants)
Afimetoran
go.drugbank.com/drugs/DB16580InvestigationalAfimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8. … [L32018, L32023] It is also is under investigation in clinical trial NCT04269356 (Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male
ABX1100
go.drugbank.com/drugs/DB17655InvestigationalABX1100 is an investigational Centyrin-siRNA conjugate that targets the Gys1 gene, which encodes glycogen synthase 1 (Gys1), an enzyme that is responsible for glycogen synthesis in the muscle. … It was first developed by Aro Biotherapeutics and is being investigated for the treatment of Pompe disease.[L45978]
Utatrectinib
go.drugbank.com/drugs/DB21295InvestigationalUtatrectinib is a small molecule drug. The usage of the INN stem '-trectinib' in the name indicates that Utatrectinib is a tropomyosin receptor kinase (TRK) inhibitor. … Utatrectinib is under investigation in clinical trial NCT01468324 (AZD7451 for Recurrent Gliomas). Utatrectinib has a monoisotopic molecular weight of 382.17 Da.
Cetyl ethylhexanoate
go.drugbank.com/drugs/DB11349InvestigationalCetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. It is present in cosmetic products as a skin conditioning agent and emollient.
Synonyms: Cetyl 2-ethylhexanoate, Hexadecyl 2-ethylhexanoateMacadamia seed oil glycereth-8 esters
go.drugbank.com/drugs/DB14318InvestigationalMacadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Macadamia seed oil glycereth-8 estersALM201
go.drugbank.com/drugs/DB17206InvestigationalALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.[A254556]
Zamubafusp alfa
go.drugbank.com/drugs/DB32269InvestigationalZamubafusp alfa is an immunoglobulin-peptide fusion protein.[L55038] It consists of a humanized IgG1 and p5R which is a pan-amyloid reactive peptide.[L55038]
JUR-003
go.drugbank.com/drugs/DB33972ExperimentalJUR-003 is a small molecule drug. JUR-003 is under investigation in clinical trial NCT07824349 (JUR-003 in Adult Patients With Metastatic Prostate Cancer).