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Alaproclate
go.drugbank.com/drugs/DB13233ExperimentalDevelopment was discontinued due to concerns over hepatotoxicity observed in animal studies.
Conteltinib
go.drugbank.com/drugs/DB21262InvestigationalConteltinib has a monoisotopic molecular weight of 635.34 Da.
Osunprotafib
go.drugbank.com/drugs/DB21547InvestigationalOsunprotafib has a monoisotopic molecular weight of 385.15 Da.
Zelicapavir
go.drugbank.com/drugs/DB21662InvestigationalZelicapavir has a monoisotopic molecular weight of 549.17 Da.
Zoracopan
go.drugbank.com/drugs/DB21702InvestigationalZoracopan has a monoisotopic molecular weight of 614.16 Da.
Tozorakimab
go.drugbank.com/drugs/DB16473InvestigationalTozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions. These trials include NCT03096795 (completed; h...
AGS-16C3F
go.drugbank.com/drugs/DB17551InvestigationalAGS 16C3F is an intravenously administered, anti-ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) antibody-drug conjugate.
EGT-101
go.drugbank.com/drugs/DB17645ExperimentalEGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the human sulfamidase (SGSH) transgene.
Omaveloxolone
go.drugbank.com/drugs/DB12513ApprovedInvestigational[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress.
Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 Substrates