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Displaying results 7161 - 7170 of 10000 in total
  1. Drug

    Ronacaleret

    go.drugbank.com/drugs/DB05255
    Investigational

    Ronacaleret is a calcium-sensing receptor antagonist.

  2. Drug

    Phosmet

    go.drugbank.com/drugs/DB11448
    ExperimentalVet approved

    It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Emoxypine

    go.drugbank.com/drugs/DB19172
    Investigational

    Emoxypine is under investigation in clinical trial NCT06221826 (MEXIDOL® in the Rehabilitation Treatment of Patients With Acute Cerebral Failure).

    Categories: Compounds used in a research, industrial, or household setting
  4. Target

    20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)

    go.drugbank.com/bio_entities/BE0009795
    EnzymeHumans and other mammals

    Catalyzes the inactivation of 5alpha-DHT and progesterone converting them into 3alpha/beta-androstanediols and (20S)-hydroxypregn-4-en-3-one, respectively (PubMed:10998348, PubMed:24434280). … Catalyzes the reduction of progesterone to less potent progestogen (20S)-hydroxypregn-4-en-3-one likely regulating ligand availability for progesterone receptors (PubMed:10998348, PubMed:11013348, PubMed

    Synonyms: CHDRFunction: 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
  5. Drug

    GI-101

    go.drugbank.com/drugs/DB17243
    Investigational

    GI-101 is a bi-specific fragment crystallizable region (Fc) fusion protein containing a cluster of differentiation 80 ectodomain as an N-terminal moiety and interleukin-2 variant as a C-terminal moiety

  6. Drug

    Zelenirstat

    go.drugbank.com/drugs/DB15567
    Investigational

    Current studies have shown that zelenirstat works differently than other known cancer drugs and has high activity and positive results in breast, lung, bladder and pancreas cancers.[L9470] … Zelenirstat (PCLX-001) is a first-in-kind N-Myristoyltransferase (NMT) inhibitor being developed by [Pacylex Pharmaceuticals](https://pacylex.com).

    Synonyms: 2,6-Dichloro-N-(1,5-dimethyl-3-(2-methylpropyl)-1H-pyrazol-4-yl)-4-(2-(1-piperazinyl)-4-pyridinyl)benzenesulfonamide, 2,6-Dichloro-N-(3-isobutyl-1,5-dimethyl-1H-pyrazol-4-yl)-4-(2-(piperazin-1-yl)pyridin-4-yl)benzenesulfonamide
  7. Drug

    Vemtoberant

    go.drugbank.com/drugs/DB21607
    Investigational

    Vemtoberant has a monoisotopic molecular weight of 619.2 Da. … Vemtoberant is under investigation in clinical trial NCT05139615 (A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With

  8. Drug

    Delocamten

    go.drugbank.com/drugs/DB21711
    Investigational

    Delocamten has a monoisotopic molecular weight of 377.16 Da. … Delocamten is under investigation in clinical trial NCT06122779 (Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection

  9. Drug

    Virginiamycin

    go.drugbank.com/drugs/DB11476
    ExperimentalVet approved

    According to a USDA study, antibiotics can save as much as 30% in feed costs among young swine. … Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination and in livestock to prevent and treat infections.

  10. Drug

    Methoxy arachidonyl fluorophosphonate

    go.drugbank.com/drugs/DB02465
    Experimental

    Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. … It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range.