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Friulimicin B

Friulimicin B is a naturally occurring antibiotic produced by a micro-organism, *Actinoplanes friuliensis*. … It shows strong cidal activity against a number of Gram-positive pathogens which commonly cause serious infections in hospital patients and which are becoming more routinely acquired in the community.

3,4-Methylenedioxy-N-isopropylamphetamine

MDI-P is also a potential therapeutic agent for the treatment of the symptoms of cystic fibrosis ("CF").

Tesofensine

TGAAC94

tgAAC94 is a recombinant adeno-associated virus serotype 2 (AAV2) vector containing the cDNA for a human tumor necrosis factor receptor (TNFR)-immunoglobulin (IgG1) Fc fusion (TNFR:Fc) gene. … The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038]

AEG35156

A second-generation synthetic antisense oligonucleotide with potential antineoplastic activity. … AEG35156 selectively blocks the cellular expression of X-linked inhibitor of apoptosis protein (XIAP), a pivotal inhibitor of apoptosis that is overexpressed in many tumors.

Forodesine

Additional preliminary findings support its use for the management of some B-cell malignancies. … Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic

Seliciclib

R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated

Ridaforolimus

Trafermin

Thioctic acid tromethamine

A salt of alpha-lipoic acid and tromethamine; may be useful in treating vascular stress in patients with diabetes.