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Bremelanotide
go.drugbank.com/drugs/DB11653ApprovedBremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women.[L9635] Bremelanotide does not interact with alcohol. … [A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown.
Categories: Receptor, Melanocortin, Type 3, agonists, Receptor, Melanocortin, Type 4, agonistsEvacetrapib
go.drugbank.com/drugs/DB11655InvestigationalEvacetrapib has been used in trials studying the basic science and treatment of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Hepatic Insufficiency, and Cardiovascular Disease.
Categories: Heterocyclic Compounds, 2-RingEptacog alfa pegol (activated)
go.drugbank.com/drugs/DB11661InvestigationalA With Inhibitors. … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia
Rabusertib
go.drugbank.com/drugs/DB11662InvestigationalRabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non Small Cell Lung Cancer.
Categories: Heterocyclic Compounds, 1-RingTreosulfan
go.drugbank.com/drugs/DB11678ApprovedInvestigationalTreosulfan is a prodrug alternative to [busulfan] for myeloablative conditioning prior to hematopoietic stem cell transplantation.
Synonyms: L-threitol-1,4-dimethanesulfonateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsDaprodustat
go.drugbank.com/drugs/DB11682ApprovedInvestigationalDaprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK. … [L44963] The drug is currently under EMA review.
Synonyms: Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)-Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingIferanserin
go.drugbank.com/drugs/DB11686InvestigationalIferanserin has been investigated for the treatment of Hemorrhoids.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists2-chloroethyl-3-sarcosinamide-1-nitrosourea
go.drugbank.com/drugs/DB11688Investigational2-chloroethyl-3-sarcosinamide-1-nitrosourea has been used in trials studying the treatment of Colorectal Cancer, Brain and Central Nervous System Tumors, and Unspecified Adult Solid Tumor, Protocol Specific
Synonyms: 2-chloroethyl-3-sarcosinamide-1-nitrosourea, ACETAMIDE, 2-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)METHYLAMINO)-Ilorasertib
go.drugbank.com/drugs/DB11694InvestigationalIlorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Synonyms: 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea, 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl)urea)Categories: Heterocyclic Compounds, 1-RingIpragliflozin
go.drugbank.com/drugs/DB11698InvestigationalIpragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Categories: Heterocyclic Compounds, 1-Ring, Sodium-Glucose Transporter 2 Inhibitors