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Azlocillin
go.drugbank.com/drugs/DB01061ApprovedAzlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Categories: Penicillin G, Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidCefditoren
go.drugbank.com/drugs/DB01066ApprovedCefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Categories: Heterocyclic Compounds, 2-RingPromethazine
go.drugbank.com/drugs/DB01069ApprovedInvestigational[A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting. … Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946.
Mixtures: PROMEDYL-B LINCTUS, COPHADYL-E COUGH LINCTUSCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigational[A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901] … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].
Synonyms: 1-Hydroxy-1,1-diphosphonoethane, (1-Hydroxyethylene)diphosphonic acidTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnmechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and … in female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidinePentolinium
go.drugbank.com/drugs/DB01090ApprovedPentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
Categories: Heterocyclic Compounds, 1-RingButenafine
go.drugbank.com/drugs/DB01091ApprovedButenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols.
Synonyms: (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamineProducts: BUTEFIN %1 KREM, 15 G, BUTEFIN %1 KREM, 30 GQuinacrine
go.drugbank.com/drugs/DB01103InvestigationalAn acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biologi...
Synonyms: 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine, 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridineCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Mixtures: TUGENS 250 MG IM ENJEKSIYON ICIN TOZ ICEREN FLAKON, 1 ADET, TUGENS 750 MG IM ENJEKSIYON ICIN TOZ ICEREN FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-RingPapaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalIt is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation.
Categories: Heterocyclic Compounds, 2-RingProducts: PAPAVERIN HIDROKLORUR 0.04 G/2 ML BIOSEL AMPUL, 10 ADET, PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 10 ADET