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Displaying results 7331 - 7340 of 9313 in total
  1. Drug

    Salirasib

    go.drugbank.com/drugs/DB12681
    Investigational

    Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.

  2. Drug

    UK-432097

    go.drugbank.com/drugs/DB12691
    Investigational

    UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

  3. Drug

    DNB-001

    go.drugbank.com/drugs/DB05757
    Investigational

    DNB-001 is a first-in-class oral therapy with dual mechanism of action, which is initially being developed for the treatment of glaucoma. … In preclinical animal models, DNB-001 has demonstrated potent IOP- lowering effects as well as neuroprotective effects on the optic nerve.

  4. Drug

    Oxalic Acid

    go.drugbank.com/drugs/DB03902
    Experimental

    It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent. [PubChem]

  5. Drug

    Gemogenovatucel-T

    go.drugbank.com/drugs/DB17412
    Investigational

    Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.

    Synonyms: Gemogenovatucel-T
  6. Drug

    PAC-113

    go.drugbank.com/drugs/DB05756
    Investigational

    In vitro studies demonstrate that it has potent anti-fungal activity against the Candida albicans, including drug-resistant HIV patient isolates. … PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva.

  7. Drug

    gamma-Butyrolactone

    go.drugbank.com/drugs/DB04699
    ExperimentalIllicit

    One of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate.

  8. Drug

    Levilimab

    go.drugbank.com/drugs/DB16387
    Investigational

    Levilimab is under investigation in clinical trial NCT04227366 (Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis).

  9. Drug

    Ertiprotafib

    go.drugbank.com/drugs/DB06521
    Experimental

    Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes.

  10. Drug

    Calanolide A

    go.drugbank.com/drugs/DB04886
    Investigational

    Calanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity.