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MK-8189
go.drugbank.com/drugs/DB19153InvestigationalMK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).
Sabirnetug
go.drugbank.com/drugs/DB19438InvestigationalSabirnetug is under investigation in clinical trial NCT06335173 (A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)).
XmAb24306
go.drugbank.com/drugs/DB17526InvestigationalXmAb24306 is an investigational cancer immunotherapy. It is a heterodimeric interleukin (IL)-15/IL-15-receptor alpha (IL-15Ra) complex fused to a bispecific Fc domain.
Dubermatinib
go.drugbank.com/drugs/DB15187InvestigationalDubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).
Buntanetap
go.drugbank.com/drugs/DB15317InvestigationalBuntanetap (previously known as Posiphen) is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Wortmannin
go.drugbank.com/drugs/DB08059ExperimentalWortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).
D-1,4-dithiothreitol
go.drugbank.com/drugs/DB02184ExperimentalA reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. [PubChem]
Synonyms: D-DTT, D-1,4-dithiothreitolN-acetyl-beta-neuraminic acid
go.drugbank.com/drugs/DB04265ExperimentalAn N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Synonyms: N-acetyl-beta-D-neuraminic acidMGD-024
go.drugbank.com/drugs/DB17265InvestigationalMGD-024 is an anti-CD123/anti-CD3 bispecific DART molecule.
MEDI-547
go.drugbank.com/drugs/DB18360InvestigationalMEDI-547 is an anti-EphA1 monoclonal antibody conjugated to mcMMAF