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Displaying results 731 - 740 of 10000 in total
  1. Drug

    Ospemifene

    go.drugbank.com/drugs/DB04938
    Approved

    Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause … FDA approved on February 26, 2013.

    Synonyms: 2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol, 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  2. Drug

    Iopydone

    go.drugbank.com/drugs/DB20831
    ApprovedWithdrawn

    Iopydone is a small molecule drug. Iopydone has a monoisotopic molecular weight of 346.83 Da.

    Synonyms: 3,5-diiodo-4(1h)-pyridoneCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea

    go.drugbank.com/drugs/DB04336
    Experimental

    Synonyms: 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea
  4. Drug

    N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide

    go.drugbank.com/drugs/DB07734
    Experimental

    Synonyms: N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide
  5. Drug

    4-Deoxy-4-Amino-Beta-D-Glucose

    go.drugbank.com/drugs/DB03291
    Experimental

    Synonyms: 4-Deoxy-4-Amino-Beta-D-Glucose
  6. Drug

    4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide

    go.drugbank.com/drugs/DB03307
    Experimental

    Synonyms: 4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide
  7. Drug

    Landiolol

    go.drugbank.com/drugs/DB12212
    ApprovedInvestigational

    [A264733] Compared to other beta-blockers, landiolol possesses unique pharmacodynamic and pharmacokinetic properties, in that it has a rapid onset and short duration of action, and has a greater affinity … Landiolol is a rapid-acting beta (β)-1 adrenergic receptor blocker that blocks the positive chronotropic effect of the beta-1 selective agonist norepinephrine.

    Synonyms: [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-(4-{(2S)-2-hydroxy-3-[{2-[(morpholin-4-ylcarbonyl)amino]ethyl}amino]propoxy}phenyl)propanoate, Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl esterCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  8. Drug

    Pindolol

    go.drugbank.com/drugs/DB00960
    ApprovedInvestigational

    Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]

    Synonyms: 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-olInternational brands: Blockin L, Blocklin L
  9. Drug

    Tizanidine

    go.drugbank.com/drugs/DB00697
    ApprovedInvestigational

    Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574]. … Initially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons

    Synonyms: 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazoleInternational brands: Sirdalud MR
  10. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. … ARBs such as olmesartan have been shown in a number of large-scale clinical outcomes trials to improve cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression

    Synonyms: 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid, 4-(hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acidMixtures: OLMEDOXTAN A®, OLMETAN® A 40/5 TABLETAS RECUBIERTAS