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Displaying results 731 - 740 of 10000 in total
  1. Drug

    Arsenic trioxide

    go.drugbank.com/drugs/DB01169
    ApprovedInvestigational

    Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. … It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: ARSENICO TRIOSSIDO EG, LEUSENOX 2 MG/ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 10 ADET
  2. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    [L31548,L31553] Although hyoscyamine is marketed in the United States, it is not FDA approved.[L31548,L31553] … [A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.[A228423] Research into the action of hyoscyamine in published literature dates back to 1826.

    Mixtures: UR N-C Urinary Antiseptic, Urimar-TProducts: Ed-spaz, Hyoscyamine ER
  3. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.

    Mixtures: A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADET, A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADETCategories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 Substrates
  4. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Synonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  5. Drug

    Capecitabine

    go.drugbank.com/drugs/DB01101
    ApprovedInvestigational

    Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers.

    Synonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inhibitors
  6. Drug

    Ciclopirox

    go.drugbank.com/drugs/DB01188
    ApprovedInvestigational

    In particular, the agent is especially effective in treating Tinea versicolor. … Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.

    Mixtures: Ciclopirox 3% / Itraconazole 5% / Urea 20%, Ciclopirox 0.77% / Salicylic Acid 2%Synonyms: 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone
  7. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular

    Synonyms: (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acidMixtures: Trinomia 100 mg/20 mg/10 mg Hartkapseln, Trinomia 100 mg/20 mg/5 mg Hartkapseln
  8. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28, 2012[L6043]. … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Mixtures: ELIQUIS 30-Day Starter Pack, ELIQUIS 30-Day Starter PackCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  9. Drug

    Iron protein succinylate

    go.drugbank.com/drugs/DB11209
    Approved

    Mixtures: PR Natal 400 ec, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 20 FLK.Products: FERPLEX 40 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, FERBEST 40 MG/15 ML ORAL ÇÖZELTI ,10 FLAKON
  10. Drug

    Acetohydroxamic acid

    go.drugbank.com/drugs/DB00551
    ApprovedInvestigational

    Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. … It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.

    Synonyms: N-Hydroxyacetamide, N-AcetylhydroxylamineProducts: CIPROFLOXACINO 100 MG/10 ML INYECTABLE, CIPROFLOXACINO 100 MG / 10 ML INYECTABLE