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Relutrigine
go.drugbank.com/drugs/DB21614InvestigationalRelutrigine is a small molecule drug. The usage of the INN stem '-trigine' in the name indicates that Relutrigine is a sodium channel blocker, signal transduction modulator. … Relutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).
Alphacetylmethadol
go.drugbank.com/drugs/DB01555ExperimentalIllicitIt is used mainly in the treatment of narcotic dependence. [PubChem]
Nicotinyl alcohol
go.drugbank.com/drugs/DB04145ExperimentalIt is used in vasospasm and threatened gangrene. [PubChem]
PRX-ASL
go.drugbank.com/drugs/DB17679ExperimentalPRX-ASL is an intracellular enzyme replacement therapy designed to replace the missing or defective enzyme in patients with argininosuccinate lyase deficiency.
Endothelin-1
go.drugbank.com/drugs/DB12652InvestigationalEndothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Psilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Valdecoxib
go.drugbank.com/drugs/DB00580ApprovedWithdrawnValdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Efinopegdutide
go.drugbank.com/drugs/DB15077InvestigationalEfinopegdutide is under investigation in clinical trial NCT03606057 (A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy
Emodepside
go.drugbank.com/drugs/DB11403InvestigationalVet approvedEmodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively
Insulin-like growth factor II
go.drugbank.com/drugs/DB14472InvestigationalIt is believed to be a major fetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults. … The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood.
Synonyms: IGF-II, Insulin-like growth factor II