Endothelin-1

DB12652InvestigationalProtein Based Therapies

Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).

Mechanism: Pharmacologically active on Endothelin receptor type B and Endothelin-1 receptor
Curator reviewed
Also known as: Endothelin (porcine) · Endothelin 1 (human) · Endothelin 1 (pig) · Endothelin 1 (rat) · Human endothelin

Resolves to

Compound

UNII2K62B8Z6XFCAS117399-94-7

Targets

P24530EDNRBP25101EDNRA

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

5Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Endothelin-1, and which of those have an active Phase 3 trial?

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