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Displaying results 7491 - 7500 of 10000 in total
  1. Drug

    Etrasimod

    go.drugbank.com/drugs/DB14766
    ApprovedInvestigational

    Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P<sub>1,4,5</sub> with no detectable activity on S1P<sub>2</sub> and S1P<sub>3</sub … 2-mg daily dose regimen of etrasimod, with a 32% and 26% remission rate observed in UC 52 and UC 12 trials respectively.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  2. Drug

    Lanraplenib

    go.drugbank.com/drugs/DB14770
    Investigational

    Lanraplenib is under investigation in clinical trial NCT03285711 (Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)).

  3. Drug

    Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)

    go.drugbank.com/drugs/DB14771
    Investigational

    Polyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).

    Synonyms: Polyacrylamide (crosslinked; 2 mole percent bisacrylamide)
  4. Drug

    Camrelizumab

    go.drugbank.com/drugs/DB14776
    Investigational

    Camrelizumab is under investigation in clinical trial NCT03417895 (SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy).

  5. Drug

    Murepavadin

    go.drugbank.com/drugs/DB14777
    Investigational

    Murepavadin is under investigation in clinical trial NCT02110459 (Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment).

  6. Drug

    Gancotamab

    go.drugbank.com/drugs/DB14784
    Investigational

    Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs.

  7. Drug

    GDC-0425

    go.drugbank.com/drugs/DB14791
    Investigational

    GDC-0425 is under investigation in clinical trial NCT01359696 (A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Glepaglutide

    go.drugbank.com/drugs/DB14794
    Investigational

    Glepaglutide is under investigation in clinical trial NCT00868660 (Healthy Normal Single Ascending Dose and Crohn's Patient Multiple Ascending Dose).

  9. Drug

    Zorifertinib

    go.drugbank.com/drugs/DB14795
    Investigational

    AZD-3759 is under investigation in clinical trial NCT03360929 (Evaluate Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of AZD3759).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    SEphB4-HSA

    go.drugbank.com/drugs/DB14797
    Investigational

    SEphB4-HSA is under investigation in clinical trial NCT02495896 (Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors).