Zorifertinib

DB14795InvestigationalSmall molecule

AZD-3759 is under investigation in clinical trial NCT03360929 (Evaluate Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of AZD3759).

Mechanism: Pharmacologically active on Epidermal growth factor receptor
Curator reviewed
Formula / weight: C₂₂H₂₃ClFN₅O₃ · 459.91 g/mol (avg)
Code names: AZD-3759

Resolves to

Compound

Structure

InChIKeyMXDSJQHFFDGFDK-CYBMUJFWSA-NSMILESCOC1=C(OC(=O)N2CCN(C)C[C@H]2C)C=C2C(NC3=C(F)C(Cl)=CC=C3)=NC=NC2=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Zorifertinib, and which of those have an active Phase 3 trial?

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