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Rocakinogene sifuplasmid
go.drugbank.com/drugs/DB16316InvestigationalRocakinogene sifuplasmid is under investigation in clinical trial NCT03491683 (INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-diagnosed Glioblastoma
Masitinib
go.drugbank.com/drugs/DB11526InvestigationalVet approvedMasitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. … In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Synonyms: 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDECategories: Heterocyclic Compounds, 1-Ringp-Fluorofentanyl
go.drugbank.com/drugs/DB09177ExperimentalIllicitp-Fluorofentanyl is an opioid analgesic being an analogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. p-Fluorofentanyl was sold briefly on the US black market in the early 1980s, before … they appeared. p-Fluorofentanyl is made with the same synthetic route as fentanyl, but by substituting para-fluoroaniline for aniline in the synthesis.
Synonyms: 4-FluorofentanylCategories: Heterocyclic Compounds, 1-RingCimetropium
go.drugbank.com/drugs/DB09271InvestigationalIt is also endowed of a direct myolitic action which partially accounts for its antispasmodic activity. It has never been approved for use in the U.S. or Canada. … Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug.
Synonyms: Cimetropium ionAd5-nCoV
go.drugbank.com/drugs/DB15655Investigational[L12675,L12678] It is being developed by CanSino Biologics Inc., in partnership with the Beijing Institute of Biotechnology, who in March 2020 announced the approval of a phase I clinical trial (ChiCTR2000030906 … )[L12675] with an expected completion in December 2020.
Synonyms: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)Alofanib
go.drugbank.com/drugs/DB20918InvestigationalAlofanib is a small molecule drug. The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor. … Alofanib is under investigation in clinical trial NCT04071184 (Study of Alofanib in Patients With Metastatic Gastric Cancer). Alofanib has a monoisotopic molecular weight of 413.07 Da.
Deracoxib
go.drugbank.com/drugs/DB11395ExperimentalVet approvedDeracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. … It is sold in tablets, which have added beefy flavour to increase palatability.
Categories: Heterocyclic Compounds, 1-RingPF-232798
go.drugbank.com/drugs/DB14813InvestigationalPF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Categories: Heterocyclic Compounds, 1-RingHuman Lactoferrin Peptide hLF1-11
go.drugbank.com/drugs/DB16245InvestigationalHuman Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Synonyms: N-terminal peptide of human lactoferrin 1-11, Human lactoferrin 1-11Mitiperstat
go.drugbank.com/drugs/DB18963InvestigationalMitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.).
Synonyms: 1-({2-[(1R)-1-aminoethyl]-4-chlorophenyl}methyl)-2-sulfanylidene-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 1-[[2-[(1R)-1-aminoethyl]-4-chlorophenyl]methyl]-1,2,3,5-tetrahydro-2-thioxo-Categories: Heterocyclic Compounds, 1-Ring