p-Fluorofentanyl

DB09177ExperimentalIllicitSmall molecule

p-Fluorofentanyl is an opioid analgesic being an analogue of fentanyl developed by Janssen Pharmaceutica in the 1960s. p-Fluorofentanyl was sold briefly on the US black market in the early 1980s,...

Mechanism: Pharmacologically active on Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor
Curator reviewed
Formula / weight: C₂₂H₂₇FN₂O · 354.469 g/mol (avg)
Also known as: 4-Fluorofentanyl · Parafluorofentanyl
Code names: IDS-NF-003 · IDS-NF-003(SECT.3)

Resolves to

Compound

UNIII45R05QM0ZCAS90736-23-5ChEMBLCHEMBL2355317ChEBI61074PubChem62300

Structure

InChIKeyKXUBAVLIJFTASZ-UHFFFAOYSA-NSMILESCCC(=O)N(C1CCN(CCC2=CC=CC=C2)CC1)C1=CC=C(F)C=C1

Targets

P41143OPRD1P41145OPRK1P35372OPRM1

What you can answer from here — as of July 03, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with p-Fluorofentanyl, and which of those have an active Phase 3 trial?

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