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PRO-1562
go.drugbank.com/drugs/DB33979ExperimentalPRO-1562 is under investigation in clinical trial NCT07826689 (A Phase 1/2a Study of Oral PRO-1562 in Healthy Subjects and Patients With Relapsing Multiple Sclerosis).
Icalcaprant
go.drugbank.com/drugs/DB21651InvestigationalIcalcaprant is under investigation in clinical trial NCT06696755 (A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder … The usage of the INN stem '-caprant' in the name indicates that Icalcaprant is a kappa-opioid receptor (KOR) antagonist.
Olomorasib
go.drugbank.com/drugs/DB21697InvestigationalOlomorasib is under investigation in clinical trial NCT06890598 (Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small … The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.
Lanraplenib
go.drugbank.com/drugs/DB14770InvestigationalLanraplenib is under investigation in clinical trial NCT03285711 (Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)).
Afasevikumab
go.drugbank.com/drugs/DB14798InvestigationalAfasevikumab is under investigation in clinical trial NCT01480310 (Study to Investigate the Safety, Pharmacokinetics, and Immunogenicity of Subcutaneous MCAF5352A in Healthy Volunteers).
BIO-11006
go.drugbank.com/drugs/DB14886InvestigationalBIO-11006 is under investigation in clinical trial NCT03202394 (Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS).
Landipirdine
go.drugbank.com/drugs/DB16214InvestigationalLandipirdine is under investigation in clinical trial NCT02258152 (SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)).
Mesdopetam
go.drugbank.com/drugs/DB16229InvestigationalMesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia).
Seviprotimut-L
go.drugbank.com/drugs/DB16328InvestigationalSeviprotimut-L is under investigation in clinical trial NCT01546571 (Study of a Melanoma Vaccine in Stage Iib, Iic, and III Melanoma Patients).
Geptanolimab
go.drugbank.com/drugs/DB16417InvestigationalGeptanolimab is under investigation in clinical trial NCT03502629 (Clinical Trial in Chinese Patients of Relapsed and Refractory Peripheral T Cell Lymphoma (GB226)).