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Displaying results 7591 - 7600 of 10000 in total
  1. Drug

    (S)-acetoin

    go.drugbank.com/drugs/DB02788
    Experimental

    A product of fermentation. It is a component of the butanediol cycle in microorganisms. In mammals it is oxidized to carbon dioxide.

    Synonyms: (S)-2-acetoin, (S)-acetoin
  2. Drug

    Zibrofusidic acid

    go.drugbank.com/drugs/DB20799
    Investigational

    Zibrofusidic acid is a small molecule drug. … Zibrofusidic acid is under investigation in clinical trial NCT00626795 (Efficacy, Safety, and Tolerability of TD1414 2% Cream in Impetigo and Secondarily Infected Traumatic Lesions (SITL)).

  3. Drug

    Zosuquidar

    go.drugbank.com/drugs/DB06191
    Investigational

    Zosuquidar is a compound of antineoplastic drug candidates currently under development. It is now in "Phase 3" of clinical tests in the United States. … Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring
  4. Drug

    N-Methylmesoporphyrin

    go.drugbank.com/drugs/DB01911
    Experimental

    N-methylmesoporphyrin is a solid. This compound belongs to the porphyrins. … This medication is known to target ferrochelatase.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: N-Methylmesoporphyrin
  5. Drug

    Tylosin

    go.drugbank.com/drugs/DB11475
    ExperimentalVet approved

    Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. … It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms. Tylosin is produced as a fermentation product of Streptomyces fradiae.

    Mixtures: Tylan 40 Sulfa-G PremixSynonyms: Tylosin A
  6. Drug

    Zastumotide

    go.drugbank.com/drugs/DB14926
    Investigational

    Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known as astuprotimut-R. … It is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck).

    Synonyms: Astuprotimut R, Astuprotimut-R
  7. Drug

    Dabocemagene autoficel

    go.drugbank.com/drugs/DB17878
    Investigational

    Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797] … Dabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen.

    Synonyms: D-Fi, THE CONTROL OF A HUMAN CYTOMEGALOVIRUS (CMV) PROMO
  8. Drug

    DYNE-251

    go.drugbank.com/drugs/DB18130
    Investigational

    DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1). … It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping.

  9. Drug

    CCR5 mAb

    go.drugbank.com/drugs/DB05906
    Experimental

    CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus ( … HIV-1).

  10. Drug

    Temanogrel

    go.drugbank.com/drugs/DB05227
    Investigational

    APD791 is an oral anti-thrombotic drug candidate being evaluated in a Phase 1 clinical trial by Arena. … APD791 is intended to lower the risk of arterial thrombosis by reducing the amplification of platelet aggregation, arterial constriction and intimal hyperplasia mediated by serotonin.

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor Antagonists