Tylosin

DB11475ExperimentalVet approvedSmall molecule

Tylosin is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive organisms and a limited range of Gram-negative organisms.... Tylosin is produced as a fermentation product of Streptomyces fradiae.

Mechanism: Pharmacologically active on 23S ribosomal RNA
Curator reviewed
Formula / weight: C₄₆H₇₇NO₁₇ · 916.1001 g/mol (avg)
Also known as: Tylocine · Tylosin A

Resolves to

Compound

UNIIYEF4JXN031CAS1401-69-0ChEMBLCHEMBL42743ChEBI17658KEGGD02490

Clinical / RWD

RxNorm995505

Structure

InChIKeyWBPYTXDJUQJLPQ-VMXQISHHSA-NSMILES

CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

174Drug interactionsStructured to mechanism, not free text

2Marketed productsAcross 1 country and 2 labellers

25+ReferencesStructured and connected to the statements they support

Which companies are running trials of Tylosin, in which indications and phases, and which of those programs are still active?

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