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Levcromakalim
go.drugbank.com/drugs/DB21154InvestigationalLevcromakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Levcromakalim is a potassium channel activator, antihypertensive. … Levcromakalim has a monoisotopic molecular weight of 286.13 Da.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingLuvometinib
go.drugbank.com/drugs/DB21696InvestigationalLuvometinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Luvometinib is a tyrosine kinase inhibitor. … Luvometinib has a monoisotopic molecular weight of 665.04 Da.
Pebezertinib
go.drugbank.com/drugs/DB21705InvestigationalPebezertinib is a small molecule drug. The usage of the INN stem '-ertinib' in the name indicates that Pebezertinib is a epidermal growth factor receptor (EGFR) inhibitor. … Pebezertinib has a monoisotopic molecular weight of 497.16 Da.
Inlexisertib
go.drugbank.com/drugs/DB21713InvestigationalInlexisertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Inlexisertib is a serine/threonine kinase inhibitor. … Inlexisertib has a monoisotopic molecular weight of 535.29 Da.
Onametostat
go.drugbank.com/drugs/DB21480InvestigationalOnametostat is a small molecule drug. The usage of the INN stem '-metostat' in the name indicates that Onametostat is a histone N-methyltransferase inhibitor. … Onametostat is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring).
Categories: Heterocyclic Compounds, 1-RingGamcemetinib
go.drugbank.com/drugs/DB21624InvestigationalGamcemetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor. … Gamcemetinib is under investigation in clinical trial NCT04947579 (A Study of CC-99677 in Participants With Active Ankylosing Spondylitis).
ATL-104
go.drugbank.com/drugs/DB05670InvestigationalATL-104 is a potent mitogen for epithelial cells of the gastrointestinal tract. In animal models, ATL-104 aids regeneration of the gastrointestinal tract after treatment with chemotherapeutic agents.
Aetiocholanolone
go.drugbank.com/drugs/DB02854ExperimentalThe 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]
Brivanib
go.drugbank.com/drugs/DB11958InvestigationalBrivanib is under investigation for the treatment of HepatoCellular Carcinoma. … Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).
Categories: Heterocyclic Compounds, 1-RingIndusatumab vedotin
go.drugbank.com/drugs/DB12413InvestigationalIndusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and