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Displaying results 7611 - 7620 of 10000 in total
  1. Drug

    Patritumab deruxtecan

    go.drugbank.com/drugs/DB21996
    Investigational

    Patritumab deruxtecan is under investigation in clinical trial NCT06596694 (Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)).

  2. Drug

    SGX-001

    go.drugbank.com/drugs/DB33968
    Experimental

    SGX-001 is under investigation in clinical trial NCT07826767 (Open-label Gene Therapy Study in p47-CGD).

  3. Drug

    Coral snake (micrurus fulvius) immune globulin antivenin (equine)

    go.drugbank.com/drugs/DB13883
    Approved

    North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment of envenomation caused by North American coral snake bites. It is intravenously administered so that the antivenin binds to and neutra...

  4. Drug

    KB-141

    go.drugbank.com/drugs/DB03176
    Experimental

    An anticholesteremic agent.

  5. Drug

    GALE-301

    go.drugbank.com/drugs/DB17262
    Investigational

    GALE-301 is an investigational cancer immunotherapy. … It is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune adjuvant, granulocyte macrophage-colony stimulating factor (GM-CSF).[A254696,L44166,L44171]

  6. Drug

    Tetrahydrocannabivarin

    go.drugbank.com/drugs/DB11755
    Investigational

    Compared to THC which demonstrates its effects through weak partial agonist activity of both endocannabinoid receptors Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a … In contrast, CB2 receptors are mainly found peripherally in immune cells, lymphoid tissue, and peripheral nerve terminals [A32676].

  7. Drug

    Sagopilone

    go.drugbank.com/drugs/DB12391
    Investigational

    multidrug-resistant and paclitaxel-resistant tumor cell lines in vitro and in vivo. … Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others.

  8. Drug

    Surabgene lomparvovec

    go.drugbank.com/drugs/DB21780
    Investigational

    Surabgene Lomparvovec is under investigation in clinical trial NCT07007065 (Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity … of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)).

  9. Drug

    Enpatoran

    go.drugbank.com/drugs/DB16501
    Investigational

    It was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327). … Enpatoran (M5049) was under investigation in clinical trials for various conditions.

  10. Drug

    Enadenotucirev

    go.drugbank.com/drugs/DB14873
    Investigational

    Enadenotucirev is under investigation in clinical trial NCT02636036 (Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors).