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Displaying results 7621 - 7630 of 10000 in total
  1. Drug

    OPB-111077

    go.drugbank.com/drugs/DB16630
    Investigational

    OPB-111077 is a novel inhibitor of STAT3 and mitochondrial oxidative phosphorylation. It has demonstrated promising anticancer activity in preclinical models.

  2. Drug

    HMI-103

    go.drugbank.com/drugs/DB17684
    Investigational

    HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.

  3. Drug

    RCT1100

    go.drugbank.com/drugs/DB18830
    Investigational

    RCT1100 is an investigational mRNA-based therapeutic that aims to treat primary ciliary dyskinesia caused by pathogenic mutations in DNAI1.[L50788]

  4. Drug

    EA-230

    go.drugbank.com/drugs/DB19114
    Investigational

    EA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)).

  5. Drug

    Tiazofurine

    go.drugbank.com/drugs/DB13243
    Experimental

    Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase [A174991].

  6. Drug

    Dihydroxyacetone

    go.drugbank.com/drugs/DB01775
    Experimental

    It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent. [PubChem] … Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage.

  7. Drug

    Cenacitinib

    go.drugbank.com/drugs/DB21735
    Investigational

    Cenacitinib is a small molecule drug. The usage of the INN stem '-citinib' in the name indicates that Cenacitinib is a Janus kinase inhibitor. … Cenacitinib is under investigation in clinical trial NCT05688852 (VTX958 for the Treatment of Moderately to Severely Active Crohn's Disease).

  8. Drug

    SCIB1

    go.drugbank.com/drugs/DB18439
    Investigational

    It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells. … SCIB1 is an investigational cancer vaccine being developed by Scancell Ltd. It is being investigated for the treatment of melanoma.

  9. Drug

    Bicifadine

    go.drugbank.com/drugs/DB04889
    Investigational

    Bicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain. … Bicifadine (DOV-220075) is a nonopioid analgesic. It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile.

  10. Drug

    Salanersen

    go.drugbank.com/drugs/DB18418
    Investigational

    BIIB115 is an investigational antisense oligonucleotide in development for spinal muscular atrophy.