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Alanosine
go.drugbank.com/drugs/DB05540InvestigationalAn amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Categories: Compounds used in a research, industrial, or household settingSynonyms: L-AlanosineOnametostat
go.drugbank.com/drugs/DB21480InvestigationalOnametostat is a small molecule drug. The usage of the INN stem '-metostat' in the name indicates that Onametostat is a histone N-methyltransferase inhibitor. … Onametostat is under investigation in clinical trial NCT06788509 (A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring).
Categories: Heterocyclic Compounds, 1-RingGamcemetinib
go.drugbank.com/drugs/DB21624InvestigationalGamcemetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor. … Gamcemetinib is under investigation in clinical trial NCT04947579 (A Study of CC-99677 in Participants With Active Ankylosing Spondylitis).
Reloxiliase
go.drugbank.com/drugs/DB17653ExperimentalReloxiliase is a first-in-class, oral crystalline formulation of the oxalate-specific, microbial enzyme oxalate decarboxylase. It is being investigated for the treatment of hyperoxaluria.[A258823]
Timbetasin
go.drugbank.com/drugs/DB19119InvestigationalTimbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Synonyms: 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)thymosin .beta.4(human), Thymosin .beta.(4), 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)-Tasquinimod
go.drugbank.com/drugs/DB05861InvestigationalThe quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts
Categories: Heterocyclic Compounds, 2-RingAetiocholanolone
go.drugbank.com/drugs/DB02854ExperimentalThe 5-beta-reduced isomer of androsterone. Etiocholanolone is a major metabolite of testosterone and androstenedione in many mammalian species including humans. It is excreted in the urine. [PubChem]
Brivanib
go.drugbank.com/drugs/DB11958InvestigationalBrivanib is under investigation for the treatment of HepatoCellular Carcinoma. … Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).
Categories: Heterocyclic Compounds, 1-RingIndusatumab vedotin
go.drugbank.com/drugs/DB12413InvestigationalIndusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and
ATL-104
go.drugbank.com/drugs/DB05670InvestigationalATL-104 is a potent mitogen for epithelial cells of the gastrointestinal tract. In animal models, ATL-104 aids regeneration of the gastrointestinal tract after treatment with chemotherapeutic agents.