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CR665
go.drugbank.com/drugs/DB05155ExperimentalCR665 is the lead clinical development candidate from a series of highly selective peripheral kappa opioid receptor agonists. … In preclinical studies, CR665 was highly selective for the peripheral kappa opioid receptor. Preclinical animal studies suggest that CR665 is a potent analgesic compound.
Paquinimod
go.drugbank.com/drugs/DB13118InvestigationalThe autoimmune attack affects several different organ systems and many patients suffer from serious secondary disease symptoms such as renal disorders as the disease progresses. … Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease.
XP12B
go.drugbank.com/drugs/DB04928InvestigationalXP12B is being developed by Xanodyne Pharmaceuticals for the treatment of menorrhagia (heavy menstrual bleeding). It was granted Fast Track status for this indication by the FDA in November 2004.
IP501
go.drugbank.com/drugs/DB06450ExperimentalThe compound was developed by Indevus Pharmaceuticals. … IP-501 is an investigational antifibrotic compound being tested for the treatment of alcohol-induced liver disease and chronic hepatitis-C-induced cirrhosis.
Vincamine
go.drugbank.com/drugs/DB13374InvestigationalVincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.
V116517
go.drugbank.com/drugs/DB16060InvestigationalV116517 is under investigation in clinical trial NCT01688947 (Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Postherpetic Neuralgia (PHN)).
Mozafancogene autotemcel
go.drugbank.com/drugs/DB17723InvestigationalRP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Managlinat dialanetil
go.drugbank.com/drugs/DB05518InvestigationalCS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.
Tocofibrate
go.drugbank.com/drugs/DB19752ExperimentalThe usage of the INN stem '-fibrate' in the name indicates that Tocofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.